Researchers at SUNY Downstate Identify the growing incidence of heart valve disease, New York

Due to the increase in cases during the study period, the in-hospital death increased by 6.7 per cent a year. These deaths were associated with age, non-elective admissions, male gender, and the presence of members.During this period, admissions to New York for all causes decreased by 3,032,235 cases to 2,628,545 cases . However, hospitalizations in patients with valvular disease significantly increased at an average rate of 9.1 % per year for the period. The trend was similar to replace or repair the valve, which collectively increased by 7.8 % per year

Phyllis Supino, EdD, professor of medicine and director of clinical epidemiology and clinical research in the division of cardiovascular medicine at SUNY Downstate and lead author of the study, said: ‘Our results suggest that the country required intensive planning to do with consequences for public health of these increases to meet the growing needs of these patients. ‘

Previous research at GUMC has found that AIB1 acts as a co-activator protein for growth, such as the estrogen receptor alpha and HER2/neu, which are also often over-expressed in tumor development. ‘AIB1 and its variant is more active estrogens and HER2/neu increase in various stages of breast cancer. We knew that AIB1 Delta 3 was more active AIB1 but this study shows that we have a major functional difference between the two proteins’ , says the study of other author, Anna Riegel, PhD, professor of oncology and deputy director for education at the Lombardi Cancer Research.